Figure 3 Clinicopathological relevance of CEP78 analyzed in the TCGA cohort. (A) Association between the expression level (high or low) of CEP78 and the studied clinicopathological features. Each column indicates a case in the heatmap. Chi-square test or Fisher’s exact test p values are shown by the right side of the heatmap and those <0.05 are highlighted in red. (B) CEP78 expression in different tumor stages (Kruskal-Wallis test followed by Dunn’s multiple comparisons test). (C) CEP78 was not associated with overall survival (log-rank test). (D) CEP78 expression in different molecular subtypes (Kruskal-Wallis test followed by Dunn’s multiple comparisons test). (E) Correlation between CEP78 expression and total number of single-nucleotide variants (SNVs) (Spearman rank correlation test). (F) Correlation between CEP78 expression and neoantigen load (Spearman rank correlation test). For (B) and (D), medians and interquartile ranges are shown.