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08 September 2020: Lab/In Vitro Research

Overexpression of Linc 4930556M19Rik Suppresses High Glucose-Triggered Podocyte Apoptosis, Fibrosis and Inflammation via the miR-27a-3p/Metalloproteinase 3 () Axis in Diabetic Nephropathy

Hong Fan 1ABCE , Weiwei Zhang 2BC*

DOI: 10.12659/MSM.925361

Med Sci Monit 2020; 26:e925361

Figure 1 4930556M19Rik level was reduced in HG-stimulated podocytes. (A) Expression of 4930556M19Rik in podocytes stimulated with 30-mM glucose for 0 h, 12 h, 24 h, and 36 h was determined using qRT-PCR assay. (B) 4930556M19Rik level in podocytes induced with 0 mM, 5 mM, 15 mM and 30 mM for 36 h was detected via qRT-PCR assay. (C) Following subcellular fraction, the 4930556M19Rik level in the cytoplasmic and nuclear fractions of podocytes was examined using qRT-PCR. * P<0.05.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750