08 September 2020>: Lab/In Vitro Research
Overexpression of Linc 4930556M19Rik Suppresses High Glucose-Triggered Podocyte Apoptosis, Fibrosis and Inflammation via the miR-27a-3p/Metalloproteinase 3 () Axis in Diabetic Nephropathy
Hong Fan 1ABCE , Weiwei Zhang 2BC*DOI: 10.12659/MSM.925361
Med Sci Monit 2020; 26:e925361
Figure 1 4930556M19Rik level was reduced in HG-stimulated podocytes. (A) Expression of 4930556M19Rik in podocytes stimulated with 30-mM glucose for 0 h, 12 h, 24 h, and 36 h was determined using qRT-PCR assay. (B) 4930556M19Rik level in podocytes induced with 0 mM, 5 mM, 15 mM and 30 mM for 36 h was detected via qRT-PCR assay. (C) Following subcellular fraction, the 4930556M19Rik level in the cytoplasmic and nuclear fractions of podocytes was examined using qRT-PCR. * P<0.05.