18 September 2020: Database Analysis
Development and Validation of a Novel Immune-Gene Pairs Prognostic Model Associated with CTNNB1 Alteration in Hepatocellular Carcinoma
Junyu Huo ABCDEF , Liqun Wu AEF* , Yunjin Zang AEDOI: 10.12659/MSM.925494
Med Sci Monit 2020; 26:e925494
Figure 1 Identification of differential expressed immune-related genes (DEIRGs) between with and without CTNNB1 mutation HCC in TCGA. (A) Boxplot of immune cell infiltration in with and without CTNNB1 mutation HCC patients (P-value significant codes: 0< *** <0.001< ** <0.01< * <0.05). (B) Heatmap of DEIRGs in the significantly enriched gene sets in CTNNB1-mutant HCC. (C) The biological process Enrichment Map of DEIRGs upregulated in the WT-CTNNB1. (D) The biological process Enrichment Map of DEIRGs upregulated in the mutated-CTNNB1.