Figure 2 Profiles of 7 alternate splicing (AS) patterns and overall survival (OS)-related AS events in pancreatic ductal carcinoma (PDAC). (A) Schematic illustration of 7 AS patterns: exon skipping (ES), alternate donor site (AD), alternate acceptor site (AA), alternate promoter (AP), alternate terminator (AT), mutually exclusive exons (ME), and retained intron (RI). (B) Bar plot of counts of AS events and parent genes for the 7 AS patterns. Red bars represent OS-AS events and parent genes from univariate Cox analysis. Black and gray bars represent all AS events and corresponding parent genes in PDAC, respectively. (C) UpSet plot of intersections of the 7 patterns of AS events. One gene may have up to 4 types of AS events in the dot panel, as shown in the next to last line, which connects 4 AS events (RI, AD, AT and ES). (D) UpSet plot of intersections of the 7 patterns of OS-AS events.