Systematic Analysis of Alternative Splicing Landscape in Pancreatic Adenocarcinoma Reveals Regulatory Network Associated with Tumorigenesis and Immune Response

Jiahua Lu; Shenyu Wei; Jianying Lou; Shengyong Yin; Lin Zhou; Wu Zhang; Shusen Zheng

doi:10.12659/MSM.925733

24 July 2020 : Database Analysis

Systematic Analysis of Alternative Splicing Landscape in Pancreatic Adenocarcinoma Reveals Regulatory Network Associated with Tumorigenesis and Immune Response

Jiahua Lu^1234BCE, Shenyu Wei^5BCD, Jianying Lou^6BF, Shengyong Yin^1234DF, Lin Zhou^1234CD, Wu Zhang^78AEG*, Shusen Zheng^1234AEG

DOI: 10.12659/MSM.925733

Med Sci Monit 2020; 26:e925733

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Figure 3 Forest plots for subgroup analyses of the 7 patterns of alternative splicing (AS) events associated with overall survival (OS) in pancreatic ductal carcinoma. (A–G) Forest plots of hazard ratios for top 20 OS-AS events: exon skipping (ES), alternate donor site (AD), alternate acceptor site (AA), alternate promoter (AP), alternate terminator (AT), mutually exclusive exons (ME), and retained intron (RI). P-values are indicated by the color scale; horizontal bars represent 95% CIs.

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Systematic Analysis of Alternative Splicing Landscape in Pancreatic Adenocarcinoma Reveals Regulatory Network Associated with Tumorigenesis and Immune Response

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