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24 July 2020: Database Analysis

Systematic Analysis of Alternative Splicing Landscape in Pancreatic Adenocarcinoma Reveals Regulatory Network Associated with Tumorigenesis and Immune Response

Jiahua Lu 1234BCE , Shenyu Wei 5BCD , Jianying Lou 6BF , Shengyong Yin 1234DF , Lin Zhou 1234CD , Wu Zhang 78AEG* , Shusen Zheng 1234AEG*

DOI: 10.12659/MSM.925733

Med Sci Monit 2020; 26:e925733

Figure 8 Correlation analysis of prognostic splicing factors (SFs), alternative splicing (AS) events, and infiltrating immune cells. (A) Proportion of the 22 human immune cell subtypes in each pancreatic ductal carcinoma sample calculated with CIBERSORT. (B, C) Dual axis correlation dot plot of SFs, AS events, and infiltrating immune cells. The x-axis represents percent spliced in (PSI) values of AS events, the left y-axis represents SF mRNA expression, and the right y-axis represents relative proportions of immune cell subtypes.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750