21 November 2020 : Database Analysis
Comprehensive Analysis of Alternative Splicing Signature in Gastric Cancer Prognosis Based on The Cancer Genome Atlas (TCGA) and SpliceSeq Databases
Xiaohu Cheng1ACEG, Xianghua Li2ACE, Yimei Gu3AE, Lianbang Zhou1AE, Jingjing Tang1B, Xiang Dai1B, Heng Jiang1B, Yang Huang1B, Yingfeng Zhang1B, Tongtong Xu1B, Zhining Liu1AE*, Qihong Zhao4AEDOI: 10.12659/MSM.925772
Med Sci Monit 2020; 26:e925772
Figure 2 The landscape of aberrant alternative splicing events in GC cohort. (A) Upset plot of ASEs for the 7 different patterns, including AA as alternate acceptor site, AT as alternate terminator, ES as exon skip, AD as alternate donor site, AP as alternate promoter, ME as mutually exclusive exons, and RI as retained intron in the GC. (B) The expression heatmap of differentially expressed alternative splicing events (DEAS). (C) Volcano plots of the distribution of DEAS in the GC dataset. Red dots represent upregulated alternative splicing events whereas green dots represent downregulated ones.