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23 November 2020: Clinical Research

Altered Brain Network Centrality in Patients with Adult Strabismus with Amblyopia: A Resting-State Functional Magnetic Resonance Imaging (fMRI) Study

Kang-Rui Wu 1ABCD* , Ya-Jie Yu 1ABCD* , Li-Ying Tang 2BCDE* , Si-Yi Chen 1BCDF , Meng-Yao Zhang 1ABCD , Tie Sun 1ABCF , Shi-Nan Wu 1ABCF , Kang Yu 1BCDF , Biao Li 1BCF , Yi Shao 1ABCDEF*

DOI: 10.12659/MSM.925856

Med Sci Monit 2020; 26:e925856

Figure 3 ROC curve analysis of the DC values for altered brain regions. (A) The area under the ROC curve were 0.931, (P<0.001; 95% CI: 0.851–1.000) for LFG, RLG 0.934 (P<0.001; 95% CI: 0.857–1.000), RMOG 0.934 (P<0.001; 95% CI: 0.857–1.000), RPG 0.927 (P<0.001; 95% CI: 0.838–1.000), LPL 0.927 (P<0.001; 95% CI: 0.828–1.000). (B) The area under the ROC curve were 0.893 (P<0.001; 95% CI: 0.786–0.999) for LMFG, LAG 0.931 (P<0.001; 95% CI: 0.849–1.000), RAG 0.938 (P<0.001; 95% CI: 0.850–1.000). DC– degree centrality; ROC – receiver operating characteristic; LFG – left fusiform gyrus; RLG – right lingual gyrus; LMFG – left middle frontal gyrus; RMOG – right middle occipital gyrus; LAG – left angular gyrus; RAG – angular gyrus; RPG – right postcentral gyrus; LPL – left paracentral lobule.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750