18 June 2020: Clinical Research
Ensemble Deep Learning Model for Multicenter Classification of Thyroid Nodules on Ultrasound Images
Xi Wei 1ACDEG* , Ming Gao 2BEF , Ruiguo Yu 3BCD , Zhiqiang Liu 3BCE , Qing Gu 4BC , Xun Liu 5BC , Zhiming Zheng 6BC , Xiangqian Zheng 2BC , Jialin Zhu 1ABCDEF* , Sheng Zhang 1BDDOI: 10.12659/MSM.926096
Med Sci Monit 2020; 26:e926096
Figure 3 Performance of the EDLC-TN in identification of thyroid cancer in different datasets. (A) Performance of the EDLC-TN on the training dataset. The accuracy, sensitivity and specificity were 93.70%, 93.19%, and 94.01%, respectively. (B) Diagnostic performance of the EDLC-TN and four other state-of-the-art machine learning algorithms. The EDLC-TN demonstrated the highest value for AUC (0.941, 95% CI: 0.935–0.946), sensitivity (93.77%), specificity (94.44%), and accuracy (98.51%). (C) The performance of EDLC-TN on the external validation dataset. The EDLC-TN achieved an accuracy of 95.76%, with a sensitivity of 95.88%, a specificity of 93.75% and an AUC of 0.979 (95% CI: 0.958–0.992).