31 October 2020 : Animal Research
Effects of Drynaria Total Flavonoid on the Microstructure of the Mandible in Ovariectomized Rats
Hui Zeng1ABCDEFG*, Xubing Zhao2AB, Lin Wang1ABEF, Chengfang Tang1DF, Zixia Li1ABF, Na Xie1AB, Feng Wang1ABFDOI: 10.12659/MSM.926171
Med Sci Monit 2020; 26:e926171
Figure 5 Drynaria total flavonoids (DTF) improved the histopathological changes in rat mandibles after ovary removal. The histopathological changes of the mandible of each group were investigated by H&E staining (×100). (A) Sham group, (B) ovariectomy control (OVX) group, (C) low-dose group, (D) middle-dose group, and (E) high-dose group. The arrows indicate the osteoporotic lesions in the mandible, including abnormal bone resorption, reduced number of trabeculae, and bite-like changes.