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03 December 2020: Animal Study

Peroxiredoxin2 (Prdx2) Reduces Oxidative Stress and Apoptosis of Myocardial Cells Induced by Acute Myocardial Infarction by Inhibiting the TLR4/Nuclear Factor kappa B (NF-κB) Signaling Pathway

Hangshun Li ADEG* , Haina Yang BDF , Dandan Wang BC , Lixin Zhang CF , Tao Ma AF

DOI: 10.12659/MSM.926281

Med Sci Monit 2020; 26:e926281

Figure 1 Expression of Prdx2 in AMI rats was lower than that in the control group. (A) HE staining of rat myocardial tissue (magnification: 200×) (n=3); (B) EF and FS results of cardiac function (n=3); (C) Expression of Prdx2 in rat myocardial tissue (n=3) (magnification: 200×); (D) Western blot results of Prdx2, TLR4, p65, and p-p65 in rat myocardial tissue (n=3); (E) mRNA expression of Prdx2 and TLR4 in rat myocardial tissue (n=3). (“*” means the difference between the 2 groups was statistically significant and P<0.05).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750