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03 December 2020: Animal Study

Peroxiredoxin2 (Prdx2) Reduces Oxidative Stress and Apoptosis of Myocardial Cells Induced by Acute Myocardial Infarction by Inhibiting the TLR4/Nuclear Factor kappa B (NF-κB) Signaling Pathway

Hangshun Li ADEG* , Haina Yang BDF , Dandan Wang BC , Lixin Zhang CF , Tao Ma AF

DOI: 10.12659/MSM.926281

Med Sci Monit 2020; 26:e926281

Figure 3 Prdx2 recombinant protein reduces cardiomyocyte apoptosis in AMI rats. (A, B) IHC staining results of caspase8 and caspase9 in rat myocardial tissue (n=3) (magnification: 200×); (C) Western blot results of Bax and Bcl-2 (n=3); (D) Ratio of expression of Bax and Bcl-2 (n=3); (E) mRNA expression of caspase8, caspase9, Bax, and Bcl-2 (n=3). (“*” means the difference between the 2 groups was statistically significant and P<0.05).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750