03 December 2020>: Animal Study
Peroxiredoxin2 (Prdx2) Reduces Oxidative Stress and Apoptosis of Myocardial Cells Induced by Acute Myocardial Infarction by Inhibiting the TLR4/Nuclear Factor kappa B (NF-κB) Signaling Pathway
Hangshun Li ADEG* , Haina Yang BDF , Dandan Wang BC , Lixin Zhang CF , Tao Ma AFDOI: 10.12659/MSM.926281
Med Sci Monit 2020; 26:e926281
Figure 4 Prdx2 inhibits TLR4/NF-κB signaling pathway in rat cardiomyocytes. (A) Western blot results of TLR4, p65, and p-p65 (n=3); (B) Ratio of expression of p-p65 and p65 (n=3); (C) mRNA expression of SOD1, SOD2, Bax, and Bcl-2 (n=3); (D, E) IHC staining results of SOD1 and caspase8 in rat myocardial tissue (n=3) (magnification: 200×). (“*” means the difference between the 2 groups was statistically significant and P<0.05).