18 November 2020 : Animal Research
Reduced Amygdala Microglial Expression of Brain-Derived Neurotrophic Factor and Tyrosine Kinase Receptor B (TrkB) in a Rat Model of Poststroke Depression
Han-xiao Zhu1ACE, Li-jing Cheng1ABCE, Ri-wei Ou Yang1CD, Yang-yang Li1CDF, Jian Liu1BCD, Dan Dai1DF, Wei Wang1BF, Ning Yang1BDF, Yun Li2AG*DOI: 10.12659/MSM.926323
Med Sci Monit 2020; 26:e926323
Figure 1 Behavioral testing results in each group at different time points after CUMS. Histograms show (A) body weight (indicative of feeding behavior), (B) sucrose preference, (C) rearing activity, and (D) locomotor activity. Data are presented as mean±SE. Intergroup comparisons evaluated by 1-way ANOVA. N=10 rats/group; 1 (first day after CUMS), 2 (2 weeks), 3 (4 weeks), 4 (8 weeks). * P<0.05 versus normal control rats; @ P<0.05 versus depression model rats (isolation-housing combined with CUMS); # P<0.05 versus stroke model rats (MCAO only). ANOVA – analysis of variance; CUMS – chronic unpredictable mild stress; MCAO – middle cerebral artery occlusion.