12 October 2020>: Animal Study
Chrysophanol Protects Against Acute Heart Failure by Inhibiting JNK1/2 Pathway in Rats
Xiao-Jiang Xie 1BCDE , Chang-Qing Li 1ACF*DOI: 10.12659/MSM.926392
Med Sci Monit 2020; 26:e926392
Figure 4 Chrysophanol alleviated the oxidative stress in AHF rats. After various treatment, rats were sacrificed and myocardial tissues were obtained. (A) MDA, (B) GPx, (C) CAT Activity, and (D) SOD Activity were detected. Each experiment was repeated 3 times. Data are expressed as mean±SEM. * p<0.05, ** p<0.01 vs. sham; # p<0.05, ## p<0.01 vs. AHF; $ p<0.05, $$ p<0.01 vs. AHF+CHR. AHF – acute heart failure; CHR – chrysophanol; SP – SP600125; Be – benazepril; MDA – malondialdehyde; GPx – glutathione peroxidase; CAT – catalase; SOD – superoxide dismutase.