Figure 5 Chrysophanol alleviated the inflammation in AHF rats. After various treatment, rats were sacrificed and blood samples were collected. (A) IL-6, (B) IL-1β, (C) TNF-α, and (D) IFN-γ levels were analyzed by ELISA. Each experiment was repeated 3 times. Data are expressed as mean±SEM. * p<0.05, ** p<0.01 vs. sham; # p<0.05, ## p<0.01 vs. AHF; $ p<0.05, $$ p<0.01 vs. AHF+CHR. AHF – acute heart failure; CHR – chrysophanol; SP – SP600125; Be – benazepril; IL-6 – interleukin-6; IL-1β – interleukin-1β; TNF-α – tumor necrosis factor-α; IFN-γ – interferon-γ.