12 October 2020 : Animal Research
Chrysophanol Protects Against Acute Heart Failure by Inhibiting JNK1/2 Pathway in Rats
Xiao-Jiang Xie1BCDE, Chang-Qing Li1ACF*DOI: 10.12659/MSM.926392
Med Sci Monit 2020; 26:e926392
Figure 6 (A, B) Chrysophanol inhibited the activation of JNK1/2 pathway. After various treatments, rats were sacrificed and myocardial tissues were collected to isolate proteins. The expression levels of protein related the MAPK pathway were determined by western blot. Each experiment was repeated 3 times. Data are expressed as mean±SEM. * p<0.05, ** p<0.01 vs. sham; # p<0.05, ## p<0.01 vs. AHF; $ p<0.05, $$ p<0.01 vs. AHF+CHR. AHF – acute heart failure; CHR – chrysophanol; SP – SP600125; Be – benazepril.