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21 October 2020: Database Analysis

The Prognostic Role of Glutathione Peroxidase 1 and Immune Infiltrates in Glioma Investigated Using Public Datasets

Shigang Lv 12ABCDE* , Haitao Luo 13ABCD* , Kai Huang 12DEFG* , Xingen Zhu 12ABCEFG*

DOI: 10.12659/MSM.926440

Med Sci Monit 2020; 26:e926440

Figure 2 The correlations between glutathione peroxidase 1 (GPX1) expression, clinical characteristics, and overall survival (OS) based on The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) datasets. GPX1 expression was higher in glioblastoma than in lower-grade glioma based on the TCGA (A) and CGGA (B) dataset. High expression of GPX1 correlated with poor OS based on the TCGA (C) and CGGA (D) datasets. The associations between GPX1 expression and clinical characteristics: age (E), sex (F), 1p/19q codel status (G), isocitrate dehydrogenase (IDH) status (H), and grade (I) in the TCGA dataset; age (J), sex (K), 1p/19q codel status (L), IDH status (M), and grade (N) in the CGGA dataset. Univariate and multiple Cox regression analysis of clinicopathological features (including GPX1 expression) and OS in the TCGA (O) and CGGA (P) datasets.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750