21 October 2020 : Database Analysis
The Prognostic Role of Glutathione Peroxidase 1 and Immune Infiltrates in Glioma Investigated Using Public Datasets
Shigang Lv12ABCDE, Haitao Luo13ABCD*, Kai Huang12DEFG, Xingen Zhu12ABCEFGDOI: 10.12659/MSM.926440
Med Sci Monit 2020; 26:e926440
Figure 2 The correlations between glutathione peroxidase 1 (GPX1) expression, clinical characteristics, and overall survival (OS) based on The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) datasets. GPX1 expression was higher in glioblastoma than in lower-grade glioma based on the TCGA (A) and CGGA (B) dataset. High expression of GPX1 correlated with poor OS based on the TCGA (C) and CGGA (D) datasets. The associations between GPX1 expression and clinical characteristics: age (E), sex (F), 1p/19q codel status (G), isocitrate dehydrogenase (IDH) status (H), and grade (I) in the TCGA dataset; age (J), sex (K), 1p/19q codel status (L), IDH status (M), and grade (N) in the CGGA dataset. Univariate and multiple Cox regression analysis of clinicopathological features (including GPX1 expression) and OS in the TCGA (O) and CGGA (P) datasets.






