Figure 4 Functional annotations and predicting signaling pathways. Biological process (A), cell component (B), and molecular function (C) enrichment. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway (D). Significant different expression genes enriched in The Gene Ontology (GO) (E) and KEGG (G) pathway; GO (F) and KEGG (H) pathway cluster analysis. Malignant hallmarks enriched in high-expression glutathione peroxidase 1 phenotypes determined using gene set enrichment analysis (I).