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21 October 2020: Database Analysis

The Prognostic Role of Glutathione Peroxidase 1 and Immune Infiltrates in Glioma Investigated Using Public Datasets

Shigang Lv 12ABCDE* , Haitao Luo 13ABCD* , Kai Huang 12DEFG* , Xingen Zhu 12ABCEFG*

DOI: 10.12659/MSM.926440

Med Sci Monit 2020; 26:e926440

Figure 5 Associations between the expression of glutathione peroxidase 1 (GPX1) and immune infiltration in glioblastoma (GBM) and lower-grade glioma (LGG). Expression of GPX1 is significantly negatively associated with tumor purity and is significantly positively associated with infiltrations with the level of B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells in GBM (A). Expression of GPX1 is significantly negatively associated with tumor purity, and it is significantly positively associated with infiltrations with the level of B cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells. It has no significant associations with infiltrations with level of CD8+ T cells in LGG (B).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750