28 September 2020>: Animal Study
Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice
Yuan Li 12BCD* , Na Yao 3ACF* , Ting Zhang 3D , Fengying Guo 3B , Xiangying Niu 4F , Zhihui Wu 3E , Shaozhang Hou 3AEFG*DOI: 10.12659/MSM.926551
Med Sci Monit 2020; 26:e926551
Figure 1 Myd88 expression correlated with neurological scores and was suppressed by GA. (A, B) Immunohistochemical staining of cerebral Myd88 in each group of mice. (C) Correlation between the percentage of Myd88 positive cells and neurological scores in the D-24+GA (p=0.0069) and D-72+GA (p=0.0024) groups (n=16 each). (D, E) Correlation between cerebral Myd88 protein level, as shown by western blotting, and neurological scores in the D-24+GA (p=0.0069) and D-72+GA (p=0.0036) groups (n=16 each). Data are shown as mean±SD. The 2 ends of each horizontal line are the 2 groups being compared, * p<0.05, ** p<0.001.