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28 September 2020: Animal Study

Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice

Yuan Li 12BCD* , Na Yao 3ACF* , Ting Zhang 3D , Fengying Guo 3B , Xiangying Niu 4F , Zhihui Wu 3E , Shaozhang Hou 3AEFG*

DOI: 10.12659/MSM.926551

Med Sci Monit 2020; 26:e926551

Figure 3 Post-treatment GA ameliorated diabetes-aggravated cerebral injury. Groups of mice were sacrificed 0 h, 12 h, 24 h, 36 h, 48 h, 60 h and 72 h after tMCAO, A. TTC staining. (B) Cerebral infarction volume. (C) Neurological scores. (D) Percentage of brain water content. (E) Blood glucose concentrations. Results are presented as mean±SD. The images are representative of 6 independent experiments. The 2 ends of each horizontal line are the 2 groups being compared. * p<0.05.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750