28 September 2020 : Animal Research
Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice
Yuan Li12BCD, Na Yao3ACF, Ting Zhang3D, Fengying Guo4B, Xiangying Niu5F, Zhihui Wu3E, Shaozhang Hou3AEFG*DOI: 10.12659/MSM.926551
Med Sci Monit 2020; 26:e926551
Figure 5 GA had more potent anti-inflammatory effects on HMGB1/TLR4-Myd88/NF-κB signaling than TAK-242 and NBP. (A) Western blotting showing expression of HMGB1, TLR4, Myd88, and NF-κB in groups of mice. (B–E) Quantitation of HMGB1 (B), TLR4 (C), Myd88 (D), and NF-κB (E) proteins. (F–I) Quantitation of HMGB1 (F), TLR4 (G), Myd88 (H), and NF-κB (I) mRNAs. The 2 ends of each horizontal line are the 2 groups being compared. * p<0.05.