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13 October 2020: Animal Study

Interaction of Orexin A and Vasopressin in the Brain Plays a Role in Blood Pressure Regulation in WKY and SHR Rats

Stanisław Kowalewski ABDEF , Katarzyna Czarzasta ADEF* , Liana Puchalska CDE , Ewa Szczepańska-Sadowska ADE , Agnieszka Wsol BDE , Agnieszka Cudnoch-Jędrzejewska EFG

DOI: 10.12659/MSM.926825

Med Sci Monit 2020; 26:e926825

Figure 2 Changes in mean arterial blood pressure (ΔMABP) during ICV infusion of orexin A in saline (NaCl) or NaCl alone (A), V1aR antagonist (V1aRANT) in dimethyl sulfoxide (DMSO)or DMSO alone (B), and OXA in NaCl followed by V1aRANT in DMSO (C). SHR – spontaneously hypertensive rats; WKY – Wistar Kyoto rats. Means±SE are shown. ** p<0.01; *** p<0.001.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750