17 August 2020 : Animal Research
Omipalisib Inhibits Esophageal Squamous Cell Carcinoma Growth Through Inactivation of Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) and ERK Signaling
Dong-shan Zhu1ABCDEF, Jing-yao Dong1BCF, Yao-yao Xu2BCD, Xin-tong Zhang2BCD, Shi-bo Fu2ACEFG, Wei Liu1ACEFG*DOI: 10.12659/MSM.927106
Med Sci Monit 2020; 26:e927106
Figure 4 Omipalisib induced cell cycle arrest of Esophageal squamous cell carcinoma (ESCC) cells. (A) Representative data of 3 independent experiments in cell cycle distribution determined by flow cytometry in ESCC cells exposed to omipalisib for 24 hours. (B) Representative image of protein expression of 3 independent experiments in 4 ESCC cells exposed to omipalisib for 24 hours. (C) Density analysis of protein bands performed with ImageJ software. Plot is the average of 3 independent experiments. (* P<0.05, ** P<0.01, *** P<0.001).