05 November 2020 : Laboratory Research
Integrated Bioinformatics Analysis of Hub Genes and Pathways Associated with a Compression Model of Spinal Cord Injury in Rats
Chang Jiang1BCE, Zheng Li1BCE, Zhaoyi Wu1DEF, Yun Liang1CD, Lixia Jin1BD, Yuanwu Cao1CG, Shengcheng Wan1DG, Zixian Chen1AG*DOI: 10.12659/MSM.927107
Med Sci Monit 2020; 26:e927107
Figure 2 Differential gene screening and weighted gene coexpression network analysis. (A) A total of 1965 differential genes were screened at different time points (Sham, 1d, 3d, 5d, and 7d) after spinal cord injury (SCI). (B, C) Analysis of network topology showed that it met the scale-free topology threshold of 0.8 when β=16. (D) The heatmap of topological matrix showed the correlation network, in which each color represented a gene module.