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05 November 2020: Lab/In Vitro Research

Integrated Bioinformatics Analysis of Hub Genes and Pathways Associated with a Compression Model of Spinal Cord Injury in Rats

Chang Jiang BCE* , Zheng Li BCE* , Zhaoyi Wu DEF* , Yun Liang CD , Lixia Jin BD , Yuanwu Cao CG , Shengcheng Wan DG , Zixian Chen AG*

DOI: 10.12659/MSM.927107

Med Sci Monit 2020; 26:e927107

Figure 3 Expression trends and pathway enrichment of modules identified via WGCNA. (A–T) A total of 10 modules were split and each module was assigned a symbolic color. It was found that the modules of magenta and brown were sharply downregulated on the first day after injury, then tended to recover; the modules of blue, pink, green, grey, and red were downregulated after injury, and then rebounded upward 3 days after SCI; the modules of black and turquoise showed a continuous decrease after injury; the yellow module was sharply upregulated within 3 days after injury, and then tended to be flat. (U–X) The figures demonstrated the top 10 of pathway enrichment in blue, brown, green, and turquoise.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750