10 November 2020>: Clinical Research
Differential Levels of Endoplasmic Reticulum Stress in Peripheral Blood Mononuclear Cells from Patients with Sudden Sensorineural Hearing Loss
Zhibiao Liu 12BCDEF , Bing Fei 1BC , Xiaoping Du 3CDF , Yanhong Dai 145DG , Wandong She 145AEFG*DOI: 10.12659/MSM.927328
Med Sci Monit 2020; 26:e927328
Figure 1 Patterns of expression of protein kinase RNA-like endoplasmic reticulum kinase (PERK), eukaryotic initiation factor 2α (eIF2α), activating transcription factor 4 (ATF4), and C/EBPO homologous protein (CHOP) in peripheral blood mononuclear cells of patients with sudden sensorineural hearing loss before treatment. (A) Examples of western blot of PERK, eIF2α, ATF4, and CHOP. (B) The western blots were quantitatively analyzed. (C–F) The messenger RNA levels of PERK, eIF2α, ATF4, and CHOP were also examined with by real-time polymerase chain reaction. * P<0.05 compared with the control group.