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10 November 2020: Clinical Research

Differential Levels of Endoplasmic Reticulum Stress in Peripheral Blood Mononuclear Cells from Patients with Sudden Sensorineural Hearing Loss

Zhibiao Liu 12BCDEF , Bing Fei 1BC , Xiaoping Du 3CDF , Yanhong Dai 145DG , Wandong She 145AEFG*

DOI: 10.12659/MSM.927328

Med Sci Monit 2020; 26:e927328

Figure 2 Comparison of activating transcription factor 4 (ATF4) and C/EBPO homologous protein (CHOP) protein levels in peripheral blood mononuclear cells (PBMCs) of patients with sudden sensorineural hearing loss (SSNHL) before and after treatment. Examples of quantitative protein detection of ATF4 in PBMCs from (A) patients with SSNHL in the improved group and (B) in the unimproved group before (pre-) and after (post-) treatment. (C) The protein levels of ATF4 were quantitatively analyzed. Examples of quantitative protein detection of CHOP in PBMCs in the (D) improved group and (E) in the unimproved group before (pre-) and after (post-) treatment. (F) The protein levels of CHOP were quantitatively analyzed. * and # indicate P<0.05.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750