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13 January 2021 : Database Analysis  

Systems Pharmacology-Based Identification of Mechanisms of Action of Bolbostemma paniculatum for the Treatment of Hepatocellular Carcinoma

Lan-Lan Wang1BE, Chen Liao2C, Xiao-Qiang Li3C, Rong Dai2C, Qing-Wei Ren4B, Hai-Long Shi1C, Xiao-Ping Wang1F, Xue-Song Feng1E, Xu Chao14AG*

DOI: 10.12659/MSM.927624

Med Sci Monit 2021; 27:e927624

Figure 3 HCC-related target network. (A) 104 shared targets between TBM and HCC. (B) Component-target network of TBM for the treatment of HCC. The red circles represent components of TBM, and green hexagons represent common targets. (C) The process of topological screening of the PPI network. (D) GO enrichment analysis for 16 key targets. (E) KEGG enrichment analysis for 16 key targets. HCC – hepatocellular carcinoma; TBM – Tu Bei Mu; PPI – protein–protein interaction; GO – Gene Ontology platform; KEGG – Kyoto Encyclopedia of Genes and Genomes platform.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750