Downregulating Gasdermin D Reduces Severe Acute Pancreatitis Associated with Pyroptosis

Tianjiao Lin; Jingyu Song; Xinting Pan; Youdong Wan; Ziqian Wu; Shaoyan Lv; Liangyu Mi; Yunyun Wang; Fei Tian

doi:10.12659/MSM.927968

14 February 2021 : Animal Research

Downregulating Gasdermin D Reduces Severe Acute Pancreatitis Associated with Pyroptosis

Tianjiao Lin^1ABCDEF, Jingyu Song^1BCDEF, Xinting Pan^1ABCDEFG*, Youdong Wan^1CDEF, Ziqian Wu^1BCD, Shaoyan Lv^1BCD, Liangyu Mi^1BC, Yunyun Wang^1BC, Fei Tian^1BC

DOI: 10.12659/MSM.927968

Med Sci Monit 2021; 27:e927968

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Figure 3 The expression of GSDMD-N and serum levels of IL-1β and IL-18. (A) The expression of GSDMD-N in the intestine. (B) Quantitative analysis of serum IL-1β. (C) Quantitative analysis of serum IL-1. * P<0.05 vs SAP group; # P<0.05 vs NS group.

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Downregulating Gasdermin D Reduces Severe Acute Pancreatitis Associated with Pyroptosis

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