04 January 2021>: Animal Study
Effect of Parecoxib Sodium on Myocardial Ischemia-Reperfusion Injury Rats
Fangyong Wu 1AEG* , Wei Wang 2ABD , Yingying Duan 1BCF , Jia Guo 1CD , Guanhua Li 2BF , Tao Ma 2DFDOI: 10.12659/MSM.928205
Med Sci Monit 2021; 27:e928205
Figure 1 Effect of parecoxib sodium on cardiac function of rats. (A) Changes in left ventricular systolic function of rats. LVSP and +dp/dtmax were remarkably higher in the Sham group than those in the I/R group and I/R+Pare group (P<0.05). (B) Changes in left ventricular diastolic function of rats. LVEDP and −dp/dtmax were remarkably higher in the Sham group than those in the I/R group and I/R+Pare group (P<0.05). (C) Changes in weight of myocardial infarction region. The infarction area was remarkably smaller in the Sham group than that in the I/R group and I/R+Pare group (P<0.05). (* P<0.05 vs. I/R group, ** P<0.01 vs. I/R group)