04 January 2021 : Animal Research
Effect of Parecoxib Sodium on Myocardial Ischemia-Reperfusion Injury Rats
Fangyong Wu1AEG*, Wei Wang2ABD, Yingying Duan1BCF, Jia Guo1CD, Guanhua Li2BF, Tao Ma2DFDOI: 10.12659/MSM.928205
Med Sci Monit 2021; 27:e928205
Figure 5 Effects of parecoxib sodium on activity of NF-κB and Nrf-2 signaling pathways. (A, B) Relative expressions of NF-κB and Nrf-2 pathways and target genes detected via PCR. The relative expressions of NF-κB pathway and its target genes were higher in the I/R group than those in the Sham group and I/R+Pare group (P<0.05). The relative expressions of Nrf-2 pathway and its target genes were lower in the I/R group than those in the Sham group and I/R+Pare group (P<0.01). (* P<0.05 vs. I/R group, ** P<0.01 vs. I/R group).