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03 March 2021: Animal Study

A Network Pharmacology Study of the Molecular Mechanisms of in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model

Sen Ling Feng 1ACE* , Jing Zhang 2BCEF* , Hongliu Jin 1BC , Wen Ting Zhu 1BC , Zhongwen Yuan 1ABCDEFG*

DOI: 10.12659/MSM.928402

Med Sci Monit 2021; 27:e928402

Figure 6 Effect of quercetin treatment on the liver/body weight ratio. #P <0.05, ## P<0.01, ### P<0.001 vs control group; * P<0.05, ** P<0.01, *** P<0.001 vs model group. Data represent mean±SD (n=6 for each group). Groups were as follows: ursodeoxycholic acid (UCDA), control (CTR), high-dose quercetin (QueH; 200 mg/kg bodyweight), medium-dose quercetin (QueM; 100 mg/kg bodyweight), low-dose quercetin (QueL, 50 mg/kg bodyweight).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750