23 February 2021>: Animal Study
Different Responses to Identical Trauma Between BALB/C and C57BL/6 Mice
Xiuying Chen 1CDEF* , Chang Cheng 1BCD* , Wenchao Cheng 2EF , Yuhan Wang 1EF , Xuzheng Zuo 1B , Weiju Tang 1B , Zhanyang Yu 3CD , Zhihuan Yang 4B , Zhengguo Wang 4AD , Peifang Zhu 4AG* , Wen Huang 1ADG*DOI: 10.12659/MSM.928676
Med Sci Monit 2021; 27:e928676
Figure 3 Distribution and expression of Cxcl15. (A) Northern blot results of the Cxcl15 gene and GAPDH gene (internal reference) expression in C57BL/6 and BALB/C mice before injury, and 1 and 6 h after injury. The odd numbers indicate C57BL/6 mouse samples, and the even numbers indicate BALB/C mouse samples: 1–4 are samples from mice pre-injury; 5–10 are samples from mice 1 h after injury; and 11–16 are samples from mice 6 h after injury. (B) Northern blot results of the Cxcl15 gene and GAPDH gene (internal reference) expression in C57BL/6 and BALB/C mice 24 and 72 h after injury. The odd numbers indicate C57BL/6 mouse samples, and the even numbers indicate BALB/C mouse samples; 1–6 are samples from mice 24 h after injury; 7–12 are samples from mice 72 h after injury. (C) Distribution of Cxcl15 in 8 main tissues in mice. (D) Expression of Cxcl15 in bronchial epithelial cells (magnification, ×100). (E) Expression of Cxcl15 in lung tissue of mice with bronchial epithelial cell cytoplasm (magnification, ×400).