Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the CDC45 Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes

Hui-Ping Lu; Xiu-Fang Du; Jian-Di Li; Su-Ning Huang; Rong-Quan He; Hua-Yu Wu; Ming-Fen Li; Wei-Zi Wu; Ji-Tian Chen; Wei-Jia Mo; Gang Chen

doi:10.12659/MSM.928800

24 February 2021 : Clinical Research

Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the CDC45 Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes

Hui-Ping Lu^1ABCDEFG, Xiu-Fang Du^1BCDEF, Jian-Di Li^1BCDEF, Su-Ning Huang^2ADEF, Rong-Quan He^3ABDEF, Hua-Yu Wu^4ABDEF, Ming-Fen Li^5BCDEF, Wei-Zi Wu^6CDEF, Ji-Tian Chen^6BCDE, Wei-Jia Mo^1ABCDEFG, Gang Chen^1ABCDEFG*

DOI: 10.12659/MSM.928800

Med Sci Monit 2021; 27:e928800

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Figure 3 The Cdc45 expression levels for the in-house tissue microarrays. Immunohistochemistry staining to evaluate the expression of Cdc45 in hepatocellular carcinoma (HCC) and adjacent tissues. (A, B) The expression of Cdc45 was absent or weak in the non-HCC tissue (2.565±1.410). (C, D) The expression of Cdc45 was obviously high in the HCC tissue (4.635±2.051). Cdc45 was detected in the nucleus and cytoplasm. Magnification, ×20 (A, C) and ×400 (B, D).

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Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the CDC45 Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes

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