24 February 2021 : Clinical Research
Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the CDC45 Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes
Hui-Ping Lu1ABCDEFG, Xiu-Fang Du1BCDEF, Jian-Di Li1BCDEF, Su-Ning Huang2ADEF, Rong-Quan He3ABDEF, Hua-Yu Wu4ABDEF, Ming-Fen Li5BCDEF, Wei-Zi Wu6CDEF, Ji-Tian Chen6BCDE, Wei-Jia Mo1ABCDEFG, Gang Chen1ABCDEFG*DOI: 10.12659/MSM.928800
Med Sci Monit 2021; 27:e928800
Figure 8 The CDC45 genetic alterations in multiple HCC datasets. (A) The oncoprint of CDC45 in 1089 cases of hepatocellular carcinoma (HCC) from multiple datasets involved The Cancer Genome Atlas (TCGA), AMC, Inserm, MSK, and RIKEN. CDC45 was altered in 9 (1%) of the patients. (B) The alteration frequency of CDC45 in HCC and mutation was the most common alternate forms, especially in liver (AMC) and HCC (Inserm, 2015) studies.