Aminoacylase 1 (ACY-1) Mediates the Proliferation and Migration of Neuroblastoma Cells in Humans Through the ERK/Transforming Growth Factor β (TGF-β) Signaling Pathways

Zimin Chen; Jiahui Gao; Jun Sun; Zhouguang Wu; Bin Wang

doi:10.12659/MSM.928813

23 February 2021 : Laboratory Research

Aminoacylase 1 (ACY-1) Mediates the Proliferation and Migration of Neuroblastoma Cells in Humans Through the ERK/Transforming Growth Factor β (TGF-β) Signaling Pathways

Zimin Chen^1ABCEG, Jiahui Gao^2BCEF, Jun Sun^1AEF, Zhouguang Wu^1DFG, Bin Wang^1ABDEFG*

DOI: 10.12659/MSM.928813

Med Sci Monit 2021; 27:e928813

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Figure 3 Effect of Aminoacylase 1 (ACY-1) on human neuroblastoma cell apoptosis. (A, B) Flow cytometry was performed to test apoptosis in SH-SY5Y cells. (C–F) The expression of Bax, Bcl-2, and Bad in SH-SY5Y cells were detected using western blotting. * Compared to mock group; # compared to siRNA-scramble group.

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Aminoacylase 1 (ACY-1) Mediates the Proliferation and Migration of Neuroblastoma Cells in Humans Through the ERK/Transforming Growth Factor β (TGF-β) Signaling Pathways

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