Figure 1 Patterns of CD26 Expression in Intact Normal Skin and Skin Wound Models. (A) Immunohistochemical staining of CD26 in samples of excisional wounds on days 7, 14 and 21. The lower panel corresponds to the high magnification area in the upper panel. (B) Immunohistochemical staining of CD26 in burn wound samples on days 7, 14, and 21. The lower panel corresponds to the high magnification area in the upper panel. (C) The mRNA expression levels of CD26 and Col1 were significantly increased in samples of skin excisional wounds compared with normal skin (n=5). (D) The mRNA expression levels of CD26 and Col1 were significantly increased in burn wound samples compared with normal skin (n=5). (E) The proportion of CD26+ fibroblasts was significantly higher in WFs than in NFs (detected by FACS and its quantification) (n=5). Scale bar: 200 μm, t test, * P<0.05 vs Intact skin group, ** P<0.01 vs Intact skin group.