12 February 2021: Animal Study
Effects of Betulinic Acid Derivative on Lung Inflammation in a Mouse Model of Chronic Obstructive Pulmonary Disease Induced by Particulate Matter 2.5
Qianyu Yue BCDE , Xiaoli Deng BCD , Yuntao Li BCD , Yunhui Zhang ADEFG*DOI: 10.12659/MSM.928954
Med Sci Monit 2021; 27:e928954
Figure 3 Betulinic acid suppresses PM2.5-mediated promotion of oxidative markers. The PM2.5-exposed mice were treated with 2-, 5-, and 8-mg/kg doses of betulinic acid. The BALF samples were assessed for MDA, NO, NOS, and SOD levels by ELISA. * P<0.05 and ** P<0.02 vs sham group.