Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

Jiaxin Guan; Lu Gan; Di Jin; Xiaowei Wu; Luyang Cheng; Meiling Liu; Ying Fan; Jing Zhou; Hanlu Zhang; Yina Zhang; Ping Zhou

doi:10.12659/MSM.929170

20 April 2021 : Clinical Research

Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

Jiaxin Guan^1BCEF, Lu Gan^1B, Di Jin^1ACD, Xiaowei Wu^1B, Luyang Cheng^1C, Meiling Liu^1C, Ying Fan^1B, Jing Zhou^2B, Hanlu Zhang^1B, Yina Zhang^1AFG*, Ping Zhou^1FG

DOI: 10.12659/MSM.929170

Med Sci Monit 2021; 27:e929170

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Figure 5 Expression levels of hsa_circ_0021739 and hsa-miR-502-5p during osteoclastogenesis. (A) Expression levels of hsa_circ_0021739 and hsa-miR-502-5p determined during osteoclastogenesis on the days 0, 4, and 8 using reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR). (B) the expression levels of hsa_circ_0021739 and hsa-miR-502-5p determined during transfection using RT-qPCR.

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Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts

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