Se-Methylselenocysteine Alleviates Liver Injury in Diethylnitrosamine (DEN)-Induced Hepatocellular Carcinoma Rat Model by Reducing Liver Enzymes, Inhibiting Angiogenesis, and Suppressing Nitric Oxide (NO)/Nitric Oxide Synthase (NOS) Signaling Pathway

Jun Ding; Chuang Qi; Jinmao Li; Chuying Huang; Jiayao Zhang; Yong Zhang; Yi Li; Bin Fan

doi:10.12659/MSM.929255

04 August 2021 : Animal Research

Se-Methylselenocysteine Alleviates Liver Injury in Diethylnitrosamine (DEN)-Induced Hepatocellular Carcinoma Rat Model by Reducing Liver Enzymes, Inhibiting Angiogenesis, and Suppressing Nitric Oxide (NO)/Nitric Oxide Synthase (NOS) Signaling Pathway

Jun Ding^1ABCDEFG*, Chuang Qi^2BCDEF, Jinmao Li^1BCDF, Chuying Huang^2BCD, Jiayao Zhang^1BCF, Yong Zhang^1BC, Yi Li^1BCF, Bin Fan^1CF

DOI: 10.12659/MSM.929255

Med Sci Monit 2021; 27:e929255

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Figure 1 Images of liver tissues from hepatocellular carcinoma rat model and model that received 3 mg/kg se-methylselenocysteine (MSC) treatment at 2, 4, 8, and 10 weeks after treatment. The white arrows represent the tumor tissues.

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Se-Methylselenocysteine Alleviates Liver Injury in Diethylnitrosamine (DEN)-Induced Hepatocellular Carcinoma Rat Model by Reducing Liver Enzymes, Inhibiting Angiogenesis, and Suppressing Nitric Oxide (NO)/Nitric Oxide Synthase (NOS) Signaling Pathway

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