Se-Methylselenocysteine Alleviates Liver Injury in Diethylnitrosamine (DEN)-Induced Hepatocellular Carcinoma Rat Model by Reducing Liver Enzymes, Inhibiting Angiogenesis, and Suppressing Nitric Oxide (NO)/Nitric Oxide Synthase (NOS) Signaling Pathway

Jun Ding; Chuang Qi; Jinmao Li; Chuying Huang; Jiayao Zhang; Yong Zhang; Yi Li; Bin Fan

doi:10.12659/MSM.929255

04 August 2021 : Animal Research

Se-Methylselenocysteine Alleviates Liver Injury in Diethylnitrosamine (DEN)-Induced Hepatocellular Carcinoma Rat Model by Reducing Liver Enzymes, Inhibiting Angiogenesis, and Suppressing Nitric Oxide (NO)/Nitric Oxide Synthase (NOS) Signaling Pathway

Jun Ding^1ABCDEFG*, Chuang Qi^2BCDEF, Jinmao Li^1BCDF, Chuying Huang^2BCD, Jiayao Zhang^1BCF, Yong Zhang^1BC, Yi Li^1BCF, Bin Fan^1CF

DOI: 10.12659/MSM.929255

Med Sci Monit 2021; 27:e929255

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Figure 8 Se-methylselenocysteine (MSC) treatments reduced serum levels of nitric oxide (NO) and nitric oxide synthase (NOS) in rats of different groups. (A) Statistical analysis of serum NO levels. (B) Statistical analysis of serum NOS levels. # P<0.05 vs Normal control group. * P<0.05 vs Model group.

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Se-Methylselenocysteine Alleviates Liver Injury in Diethylnitrosamine (DEN)-Induced Hepatocellular Carcinoma Rat Model by Reducing Liver Enzymes, Inhibiting Angiogenesis, and Suppressing Nitric Oxide (NO)/Nitric Oxide Synthase (NOS) Signaling Pathway

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