21 April 2021 : Animal Research
Short-Term High-Intensity Treadmill Exercise Promotes Ceramide-Dependent Extracellular Vesicle Secretion in the Central Nervous System of Mice
Rui Zhang12ABCEF, Xiaoyan Liang1BC, Shi Tang1BC, Lin Song1CD, Jing Zhang1CF, Yifeng Du1AG*DOI: 10.12659/MSM.929609
Med Sci Monit 2021; 27:e929609
Figure 2 Short-term high-intensity exercise increased the levels of EV biomarkers in the mouse serum. (A) Western blot shows the indicated biomarkers in serum from mice sacrificed before exercise (control), immediately after exercise (0 min) and 90 min after exercise (90 min). (B) The serum level of TSG101 showed no significant increase (P>0.05). (C) The serum level of CD63 showed no apparent changes (P>0.05). (D) The HSC70 level was markedly higher after exercise than before exercise (p<0.01); n=8/group. Data are expressed as the mean±SD; * P<0.05, ** P<0.01 using one-way ANOVA with the Bonferroni post-test.