06 August 2021: Lab/In Vitro Research
Human Umbilical Cord Mesenchymal Stem Cell Therapy Mitigates Interstitial Cystitis by Inhibiting Mast Cells
Yuancheng Xu ABDEF* , Fei Yang BC , Juncong Xie BC , Wenbiao Li BC , Bolong Liu BD , Jialiang Chen BC , Honglu Ding BC , Jiarong Cai EFDOI: 10.12659/MSM.930001
Med Sci Monit 2021; 27:e930001
Figure 2 Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) restored bladder function in the interstitial cystitis (IC)-induced rat model. (A) Conscious cystometry results. (B) Micturition intervals of the IC+MSC group (307±35 s) were significantly longer than that of the IC+PBS group (217±37 s; P<0.01, with post hoc adjustment), but similar to that of the sham group (319±18 s; P=0.27, with post hoc adjustment). ** P<0.01 vs sham group; ## P<0.01 vs IC+PBS group.