06 August 2021 : Animal Research
Human Umbilical Cord Mesenchymal Stem Cell Therapy Mitigates Interstitial Cystitis by Inhibiting Mast Cells
Yuancheng Xu1ABDEF*, Fei Yang1BC, Juncong Xie1BC, Wenbiao Li1BC, Bolong Liu1BD, Jialiang Chen1BC, Honglu Ding1BC, Jiarong Cai1EFDOI: 10.12659/MSM.930001
Med Sci Monit 2021; 27:e930001
Figure 2 Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) restored bladder function in the interstitial cystitis (IC)-induced rat model. (A) Conscious cystometry results. (B) Micturition intervals of the IC+MSC group (307±35 s) were significantly longer than that of the IC+PBS group (217±37 s; P<0.01, with post hoc adjustment), but similar to that of the sham group (319±18 s; P=0.27, with post hoc adjustment). ** P<0.01 vs sham group; ## P<0.01 vs IC+PBS group.