06 August 2021>: Lab/In Vitro Research
Human Umbilical Cord Mesenchymal Stem Cell Therapy Mitigates Interstitial Cystitis by Inhibiting Mast Cells
Yuancheng Xu ABDEF* , Fei Yang BC , Juncong Xie BC , Wenbiao Li BC , Bolong Liu BD , Jialiang Chen BC , Honglu Ding BC , Jiarong Cai EFDOI: 10.12659/MSM.930001
Med Sci Monit 2021; 27:e930001
Figure 5 β-Hexosaminidase secretion was evaluated by ELISA. (A) β-Hexosaminidase assay: the concentration of β-hex released from the sensitized RBL-2H3 cells was significantly higher than that of normal RBL-2H3 cells. ** P<0.01 vs sham group. (B, C) Histamine and 5-hydroxytryptamine (5-HT) levels in the C48+MSC group were significantly lower than in the C48 group. ** P<0.01 vs sham group; ## P<0.01 vs C48 group.