10 May 2021 : Clinical Research
Functional Magnetic Resonance Imaging of Language Following Constraint-Induced Aphasia Therapy Primed with Intermittent Theta Burst Stimulation in 13 Patients with Post-Stroke Aphasia
Jane B. Allendorfer1BCDEF*, Rodolphe Nenert1BCDE, Sangeeta Nair1CDE, Jennifer Vannest2ABDE, Jerzy P. Szaflarski13ABCDEFGDOI: 10.12659/MSM.930100
Med Sci Monit 2021; 27:e930100
Figure 1 Overview of study recruitment and procedures. (A) CONSORT flow diagram outlining recruitment of subjects who suffered a left middle cerebral artery stroke and participated in the magnetic resonance imaging (MRI) study before and after treatment with constraint-induced aphasia therapy (CIAT) primed with intermittent theta burst stimulation (iTBS; modified after Szaflarski et al (2018) [3]). (B) Schematic of the open label study procedures. Participants performed language testing and MRI at baseline within 1 week of treatment initiation (T1), within 1 week of treatment completion (T2), and again after 12 weeks following treatment completion (T3).