Effect of Fluorofenidone Against Paraquat-Induced Pulmonary Fibrosis Based on Metabolomics and Network Pharmacology

Feiya Jiang; Tongtong Wang; Sha Li; Yu Jiang; Zhuo Chen; Wen Liu

doi:10.12659/MSM.930166

01 April 2021 : Animal Research

Effect of Fluorofenidone Against Paraquat-Induced Pulmonary Fibrosis Based on Metabolomics and Network Pharmacology

Feiya Jiang^1AE, Tongtong Wang^1B, Sha Li^2D, Yu Jiang^3C, Zhuo Chen^4F, Wen Liu^1AG*

DOI: 10.12659/MSM.930166

Med Sci Monit 2021; 27:e930166

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Figure 10 Fluorofenidone attenuated pulmonary fibrosis by upregulating autophagy. (A), Effects of fluorofenidone on the expression of fibrosis-related proteins in rat lung tissue. (B), Effects of fluorofenidone on the expression of autophagy-related proteins in rat lung tissue. * P<0.05 vs the control group; ** P<0.01 vs the control group; # P<0.05 vs the PQ group.

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Effect of Fluorofenidone Against Paraquat-Induced Pulmonary Fibrosis Based on Metabolomics and Network Pharmacology

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