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13 April 2021 : Clinical Research  

Intrahepatic Cholestasis of Pregnancy Is Associated with Reduced Nitric Oxide Synthase (iNOS) in Plasma and Placentas: A Pilot Study

Yun Wang1G, Liping Zhu1D, Duo Xu2F, Liying Gao1C, Yongmei Li1E, Baoquan Liang1BC, Xiaoqian Zhang1B, Yongfei Yue1AC*

DOI: 10.12659/MSM.930176

Med Sci Monit 2021; 27:e930176

Figure 4 Protein and mRNA levels of inducible nitric oxide synthase (iNOS) in placentas from the control and cholestasis of pregnancy (ICP) groups. (A) Protein expression (western blotting) of iNOS in placental tissues. (B) Quantitative reverse transcription-polymerase chain reaction (RT-PCR) showed different mRNA levels of iNOS in placental tissue from the 2 groups (* P<0.05). (C) Quantitation of western blotting (mean±SD). Western blotting showed iNOS protein levels in placental tissue from the 2 groups (* P<0.05).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750