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22 July 2021: Database Analysis

Identification of Key Genes and Underlying Mechanisms in Acute Kawasaki Disease Based on Bioinformatics Analysis

Side Gao BCDEF , Wenjian Ma BCD , Xuze Lin BCD , Sizhuang Huang BC , Mengyue Yu AG*

DOI: 10.12659/MSM.930547

Med Sci Monit 2021; 27:e930547

Figure 8 Validation of the hub gene expression changes in KD before and after IVIG treatment. Expression of the identified 10 hub genes in pre- and post-IVIG treatment KD were compared using GSE16797, and 6 genes were significantly downregulated after IVIG. (A) ITGAX. (B) LILRB2. (C) C3AR1. (D) MAPK14. (E) TLR5. (F) MYD88. The x-axis shows different groups and y-axis shows a log2 transformation of gene expression. * P<0.05, ** P<0.01.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750